Structure of the Gametes A complex dialogue exists between egg and sperm. The egg activates the sperm metabolism that is essential for fertilization, and the sperm reciprocates by activating the egg metabolism needed for the onset of development. Gametes are the haploid sex cells, fondly referred to as sperm and eggs, which combine during fertilization to kick-off the formation of a new organism. The production of gametes is the first step of sexual reproduction. The name gamete was introduced by the Austrian biologist Gregor Mendel. Gametes carry half the genetic information of an individual, one ploidy of each type, and are created through meiosis. Oogenesis is the process of female gamete formation in animals. In short a gamete is an egg (female gamete) or a sperm (male gamete). This is an example of anisogamy or heterogamy, the condition in which females and males produce gametes of different sizes (this is the case in humans; the human ovum has approximately 100,000 times the volume of a single human sperm cell ). Formation of the Female Gamete. At the end of meiosis I, two cells result, each with a full set of chromosomes. These cells again go through a process of duplicating and splitting, but this time, the resulting cells only have half of the chromosomes. The resulting cells of meiosis are the gametes.
From here on, we're going to focus on the world of sexual reproduction. To do that, we'll discuss its star players: the gametes. Gametes are the haploid sex cells, fondly referred to as sperm and eggs, which combine during fertilization to kick-off the formation of a new organism. The production of gametes is the first step of sexual reproduction.
Basic MeiosisAn important part of gamete production is meiosis. In this process, diploid cells get the karate chop to turn them into haploid cells. Although sperm and egg production differ in many ways, meiosis is critical to both processes. The basic process of meiosis is described a little bit in another Shmoop guide, but we will give you a quick rundown again right here because it's an important part of gamete formation.Meiosis begins with a regular diploid cell. Remember, diploid means two full 'sets' of chromosomes. We'll use the cell in the image below as an example. The parent cell has two sets of chromosomes (2n). In an oversimplified nutshell, here's what happens.
Count the chromosomes. Before DNA duplication, we have one cell with two copies of two chromosomes (for four total). Through the process of meiosis, we end up with four cells with one copy of two chromosomes (for two total). Neat, huh? Gamete Diversity and RecombinationWe've already learned that sexual reproduction leads to greater genetic diversity, because the offspring have a genome that's a combination of genes from two parents. Meiosis is key to this increase in diversity, because each parent produces a variety of gametes. After all, if every gamete from a parent were the same, then all siblings would be identical twins.Gametes are governed by a couple of laws:
RecombinationDuring meiosis, bits of DNA are swapped between chromosomes in a process called recombination. This means that the resulting chromosomes are unique, and are no longer just like mom or just like dad. Now they're more like mofather and famother hybrids. This is important because it helps genes to get switched around so that all offspring are completely unique.Let's think about how this works. Pretend there's a dude named Larry, and he has some chromosomes. On one particular chromosome, there's a gene for eye color and a gene for nose size. The chromosome Larry got from his mother has the alleles for green eyes and a giant (we're talking obscenely huge) nose. The chromosome from his father has the alleles for brown eyes and a tiny nose. Larry wound up with brown eyes and an unfortunately large nose, because those alleles are dominant, but that's another story. Larry's parents united their gametes and produced a Larry, who expresses a combination of both of their genes. When Larry produces gametes of his own, those gametes are going to recombine his genes into new combinations that never before existed. If there was no recombination during meiosis then the brown eyes allele (from his dad) and giant nose allele (from his mom) would be permanently located on separate versions of his chromosomes. If they're never on the same chromosome, then they can't ever be in the same gamete (since each gamete only gets one copy of each chromosome). Larry's children would never inherit his brown eyes and giant nose. Luckily, recombination means that the brown eyes and the green eyes could swap position and create a chromosome with both brown eyes and a giant nose. Recombination is what makes it possible for Larry's offspring to have a mix of Larry's genes. Of course, when Larry meets Larry-Etta and their gametes fuse, there will be another set of genes thrown into the mix, which might overshadow that giant schnoz. Sperm ProductionThe gamete cells produced by males are called spermatozoa, or sperm for short (we tried to call them 'tozoa' instead, but it never caught on). The process by which sperm are produced is called spermatogenesis. The headquarters for sperm production are the testicles or testes.Behold, sperm, the male gamete. Each sperm is about 50 micrometers from head to tail. To put that into perspective, a human hair is about 100 micrometers in diameter. Image from here. Most animals have two testicles, although some jawless fish only have one. Without a jaw, two testicles just wouldn't look right. Spermatogenesis occurs in an area of the testes called the seminiferous tubules. If you were to unwind a human's seminiferous tubules, they would be about 20 feet long. Be sure to ask for permission first. The cells that want to be gametes when they grow up are called germ cells. The germ cells for males are called spermatogonia and they're located in the seminiferous tubules. These germ cells can either 1) undergo mitosis to create more spermatogonia, or 2) they can undergo meiosis and develop into gametes. Towards the end of development, sperm grow a small tail or flagellum for swimming. They also develop a sac on their heads called an acrosome that contains special enzymes to eat through the egg's wall. Tasty. At the appropriate moment, the sperm are ejaculated from the body. They are immersed in a combination of helpful liquids that provide nutrition and structural support to help them on their quest to fertilize an egg. It's like the Fellowship of the Sperm. Most animals don't begin spermatogenesis until puberty, and after that point sperm production is a continuous event throughout the course of a male's life. The testes might get bored, but they have no choice. Sperm production is controlled by hormones. Special testosterone-producing Leydig cells in the testes are stimulated by hormones signals sent from the brain and pituitary gland. The length of time to complete spermatogenesis differs between animals, but in mammals it's between 30â78 days. In humans, it takes approximately 74 days from start to finish. This means that spermatogonia that start meiosis today might be fertilizing an egg 74 days from now. Egg ProductionThe female gamete is called an oocyte, or egg. The process of egg production is called oogenesis. Oogenesis occurs in the ovaries, which are the female equivalent of the testes. Ooooh boy, that's a lot of o's.Oogenesis varies greatly between animals. Some animals produce a single egg at a time, while others produce millions of eggs at a time. We'll describe oogenesis as it occurs in most mammals and then talk about other animals. Oogenesis in MammalsWhen a female mammal is born, her ovaries are filled with a finite number (this means a set-in-stone, limited number) of small sacs called follicles. Each follicle contains a singleThe process of oogenesis. Image from here. Primary oocytes wait ever so patiently in the beginning stage of meiosis for the right time to complete the process, and that right time is called puberty. During puberty, certain hormones tell them to wake up and start dividing. A primary oocyte then undergoes the first split of meiosis. Oocytes don't split equally. Instead, one large cell and one teensy tiny cell form. The tiny cell is called a polar body (first polar body in the image above), which serves as a chromosome dump. It allows the egg to get rid of the excess genetic material without splitting the nutrient rich cytoplasm it needs for development. The polar body may divide by meiosis again, but these polar bodies deteriorate over time. The remaining large cell is called a secondary oocyte. Secondary oocytes are released from the ovary during ovulation with a dream of being fertilized. If they do meet a handsome sperm, then they quickly undergo the second meiotic division. It's an uneven split again, and another polar body forms. This means there are now two polar bodies (or three if the first polar body underwent the second split of meiosis). Oogenesis in Other AnimalsThis process can be slightly different in other animals:
HermaphroditesSperm are typically produced by males, and eggs are traditionally produced by females, but that isn't always the case. There are animals that can produce both types of gametes. These animals are called hermaphrodites.Gamete Formation Diagram DefinitionSome hermaphrodites can always produce both gametes, and they play both the male and the female roles at the same time. Snails, slugs, and earthworms fit into this category. Self-fertilization can occur in some of these species, although mating with a partner is still common (and beneficial to promote genetic diversity). This can lead to either one or both partners becoming fertilized. Talk about a brother from another mother/father. Other types of hermaphrodites are born either male or female, but they can switch sexes later in life. Many species of fish, including clownfish, can do this. Apparently, dinosaurs at Jurassic Park can do this too. The change often occurs to maintain a social dynamic that is dependent upon a set proportion of males and females. Hermaphroditic clownfish. If Nemo's father had waited awhile, he could have been a female clownfish instead. Image from here. Brain SnackGametes are a delicacy in many cultures. Humans and other animals eat a lot of eggs: turtle eggs, fish eggs, chicken eggs, etc. Since chickens lay their eggs whether they're fertilized or not, most of the chicken eggs eaten by humans are unfertilized. Most of themâ¦
A gamete (/ËɡæmiËt/; from Ancient Greek γαμεÏή gamete from gamein 'to marry'[1]) is a haploidcell that fuses with another haploid cell during fertilization in organisms that sexually reproduce. In species that produce two morphologically distinct types of gametes, and in which each individual produces only one type, a female is any individual that produces the larger type of gameteâcalled an ovumâ and a male produces the smaller tadpole-like typeâcalled a sperm. In short a gamete is an egg cell (female gamete) or a sperm (male gamete). This is an example of anisogamy or heterogamy, the condition in which females and males produce gametes of different sizes (this is the case in humans; the human ovum has approximately 100,000 times the volume of a single human sperm cell[2][3]). In contrast, isogamy is the state of gametes from both sexes being the same size and shape, and given arbitrary designators for mating type. The name gamete was introduced by the Austrian biologist Gregor Mendel. Gametes carry half the genetic information of an individual, one ploidy of each type, and are created through meiosis.
Oogenesis is the process of female gamete formation in animals. This process involves meiosis (including meiotic recombination) occurring in the diploid primary oocyte to produce the haploid ovum. Spermatogenesis is the process of male gamete formation in animals. This process also involves meiosis occurring in the diploid primary spermatocyte to produce the haploid spermatozoon.
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Dissimilarity[edit]
In contrast to a gamete, the diploid somatic cells of an individual contain one copy of the chromosome set from the sperm and one copy of the chromosome set from the egg cell; that is, the cells of the offspring have genes expressing characteristics of both the father and the mother. A gamete's chromosomes are not exact duplicates of either of the sets of chromosomes carried in the diploid chromosomes, and often undergo random mutations resulting in modified DNA and subsequently, new proteins and phenotypes.[citation needed]
Sex determination in humans and birds[edit]
In humans, a normal ovum can carry only an X chromosome (of the X and Y chromosomes), whereas a sperm may carry either an X or a Y (a non-normal ovum can end up carrying two or no X chromosomes, as a result of an irregularity at either of the two stages of meiosis, while a non-normal sperm cell can end up carrying either no sex-defining chromosomes, an XY pair, or XX pair as a result of the forementioned reason); ergo the male sperm determines the sex of any resulting zygote, if the zygote has two X chromosomes it will develop into a female, if it has an X and a Y chromosome, it will develop into a male.[4] For birds, the female ovum determines the sex of the offspring, through the ZW sex-determination system.[4]
Artificial gametes[edit]
Artificial gametes, also known as In vitro derived gametes (IVD), stem cell-derived gametes (SCDGs), and In vitro generated gametes (IVG), are gametes derived from stem cells. Research shows that artificial gametes may be a reproductive technique for same-sex male couples, although a surrogate mother would still be required for the gestation period.[5] Women who have passed menopause may be able to produce eggs and bear genetically related children with artificial gametes.[5] Robert Sparrow wrote, in the Journal of Medical Ethics, that embryos derived from artificial gametes could be used to derive new gametes and this process could be repeated to create multiple human generations in the laboratory.[6] This technique could be used to create cell lines for medical applications and for studying the heredity of genetic disorders.[6] Additionally, this technique could be used for human enhancement by selectively breeding for a desired genome or by using recombinant DNA technology to create enhancements that have not arisen in nature.[6]
Plants[edit]
Plants which reproduce sexually also have gametes. However, since plants have an alternation of diploid and haploid generations some differences exist. In flowering plants the flowers use meiosis to produce a haploid generation which produce gametes through mitosis. The female haploid is called the ovule and is produced by the ovary of the flower. When mature the haploid ovule produces the female gamete which are ready for fertilization. The male haploid is pollen and is produced by the anther, when pollen lands on a mature stigma of a flower it grows a pollen tube down into the flower. The haploid pollen then produces sperm by mitosis and releases them for fertilization.
Notes and references[edit]
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